Recombinant human Insulin-like Growth Factor-binding protein 5 (IGF-binding protein 5) (BBP-370)

$275.00


Human IGF-Binding protein 5 is produced in genetically engineered yeast, and purified by affinity chromatography and HPLC. This recombinant protein size is 30 kDa.
Alternative names IBP 5, IBP-5, IBP5, IBP5_HUMAN, IGF binding protein 5, IGF BP5, IGF-binding protein 5, IGFBP 5, IGFBP-5, IGFBP5, Insulin like growth factor binding protein 5, Insulin-like growth factor-binding protein 5
Type Recombinant.
Source Yeast


Description

Product name Recombinant human Insulin-like Growth Factor-binding protein 5 (IGF-binding protein 5) (BBP-370)
Catalog number BBP-370-2
Brand family Austral Biologicals
Product type Proteins and Peptides


Biological Information

Purity Over 90% (SDS gel electrophoresis)
Purification method Purified by affinity chromatography and reverse-phase HPLC


Target

SwissProt ID Link P24593
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors
Subcellular Location Secreted
Tissue Specificity Osteosarcoma, and at lower levels in liver, kidney and brain
Sequence Similarities Contains 1 IGFBP N-terminal domain.
Contains 1 thyroglobulin type-1 domain


Poduct Presentation

Form Lyophilized powder


Storage and Shipping Information

Storage Store at +4 ºC. Reconstitution is best in water or buffer near neutral pH. After reconstitution, storage in aliquots at -80 ºC is recommended


References and Citations

Citations 1. Rechler M.M. and Brown A.L. (1992) Growth Regulation, 2, 55.
2. Modern Concepts of Insulin-Like Growth Factor. Ed. E. Martin Spencer, M.D. (1991). Elsevier Science Publ., pages 311-415