Anti-AZU1 antibody (AA36101)

$187.00


Alternative names Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, AZU1, CAP7_HUMAN, P20160, 566
Source 251
Species Reactivity Human
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AZU1 antibody (AA36101)
Catalog number AA36101
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Azurocidin antibody, Cationic antimicrobial protein CAP37 antibody, Heparin-binding protein antibody, HBP antibody, AZU1 antibody, CAP7_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target

Target Name AZU1
SwissProt ID Link P20160
Function This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G.
Subcellular Location Cytoplasmic granule. Cytoplasmic granules of neutrophils.
Subunit Structure Monomer.
Sequence Similarities Belongs to the peptidase S1 family. Elastase subfamily. Contains 1 peptidase S1 domain.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.