Anti-AVIL antibody (AA28907)

$287.00


Alternative names Advillin, p92, AVIL, AVIL_HUMAN
Species Reactivity Human, Mouse
Applications WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AVIL antibody (AA28907)
Catalog number AA28907
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Advillin antibody, p92 antibody, AVIL antibody, AVIL_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human AVIL
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:1000 - 1:2000
Purification method Purified by affinity chromatography


Target

Target Name AVIL
SwissProt ID Link O75366
Function Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.
Subcellular Location Cytoplasm, cytoskeleton. Cell projection. Cell projection, axon.
Tissue Specificity Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus.
Subunit Structure Associates (via C-terminus) with actin. Interacts with SCARF1. Interacts with F-actin.
Sequence Similarities Belongs to the villin/gelsolin family. Contains 6 gelsolin-like repeats. Contains 1 HP (headpiece) domain.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.