Anti-ATP6V1B1 antibody (AA38183)


Alternative names V-type proton ATPase subunit B, kidney isoform, V-ATPase subunit B 1, Endomembrane proton pump 58 kDa subunit, Vacuolar proton pump subunit B 1, ATP6V1B1, ATP6B1, VATB, VPP3, VATB1_HUMAN, P15313, 525
Source 513
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Product name Anti-ATP6V1B1 antibody (AA38183)
Catalog number AA38183
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names V-type proton ATPase subunit B, kidney isoform antibody, V-ATPase subunit B 1 antibody, Endomembrane proton pump 58 kDa subunit antibody, Vacuolar proton pump subunit B 1 antibody, ATP6V1B1 antibody, ATP6B1 antibody, VATB antibody, VPP3 antibody, VATB1_HUMAN antibody

Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target Name ATP6V1B1
SwissProt ID Link P15313
Function Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Subcellular Location Endomembrane system; Peripheral membrane protein. Endomembrane.
Involvement in Disease Renal tubular acidosis, distal, with progressive nerve deafness: An autosomal recessive disease characterized by the association of renal distal tubular acidosis with sensorineural hearing loss. Distal renal tubular acidosis is characterized by reduced ability to acidify urine, variable hyperchloremic hypokalemic metabolic acidosis, nephrocalcinosis, and nephrolithiasis. It is due to functional failure of alpha-intercalated cells of the cortical collecting duct of the distal nephron, where vectorial proton transport is required for urinary acidification. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Expressed in the cochlea and endolymphatic sac.
Subunit Structure V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein). Forms a complex with SLC9A3R1 and SCL4A7.
Sequence Similarities Belongs to the ATPase alpha/beta chains family.

Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3

Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.