Anti-ATP5J antibody (AA29957)

$287.00


Alternative names ATP synthase-coupling factor 6, mitochondrial, ATPase subunit F6, ATP5J, ATP5A, ATPM, ATP5J_HUMAN, P18859, 522
Source 108
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ATP5J antibody (AA29957)
Catalog number AA29957
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names ATP synthase-coupling factor 6, mitochondrial antibody, ATPase subunit F6 antibody, ATP5J antibody, ATP5A antibody, ATPM antibody, ATP5J_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ATP5J
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:200-1:2000 IHC 1:50-1:200
Purification method Purified by affinity chromatography


Target

Target Name ATP5J
SwissProt ID Link P18859
Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
Subcellular Location Mitochondrion. Mitochondrion inner membrane.
Subunit Structure F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) seems to have nine subunits: a, b, c, d, e, f, g, F6 and 8 (or A6L). Component of an ATP synthase complex composed of ATP5F1, ATP5G1, ATP5E, ATP5H, ATP5I, ATP5J, ATP5J2, MT-ATP6, MT-ATP8, ATP5A1, ATP5B, ATP5D, ATP5C1, ATP5O, ATP5L, USMG5 and MP68.
Sequence Similarities Belongs to the eukaryotic ATPase subunit F6 family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.