Anti-ATP2C1 antibody (AA26690)

$187.00


Alternative names Calcium-transporting ATPase type 2C member 1, ATPase 2C1, EC 3.6.3.8, ATP-dependent Ca(2+) pump PMR1, ATP2C1, KIAA1347, PMR1L, HUSSY-28, AT2C1_HUMAN, P98194, 27032
Source 919?888?
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ATP2C1 antibody (AA26690)
Catalog number AA26690
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Calcium-transporting ATPase type 2C member 1 antibody, ATPase 2C1 antibody, EC 3.6.3.8 antibody, ATP-dependent Ca(2+) pump PMR1 antibody, ATP2C1 antibody, KIAA1347 antibody, PMR1L antibody, HUSSY-28 antibody, AT2C1_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target

Target Name ATP2C1
SwissProt ID Link P98194
Function This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium.
Subcellular Location Golgi apparatus membrane; Multi-pass membrane protein.
Involvement in Disease Hailey-Hailey disease: Autosomal dominant disorder characterized by persistent blisters and suprabasal cell separation of the epidermis, due to impaired keratinocyte adhesion. Patients lacking all isoforms except isoform 2 have HHD. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Found in most tissues except colon, thymus, spleen and leukocytes. Most abundant in keratinocytes and kidney.
Sequence Similarities Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.