Anti-ATP1B1 antibody (AA35382)

$187.00


Alternative names Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1, ATP1B1, ATP1B, AT1B1_HUMAN
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ATP1B1 antibody (AA35382)
Catalog number AA35382
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Sodium/potassium-transporting ATPase subunit beta-1 antibody, Sodium/potassium-dependent ATPase subunit beta-1 antibody, ATP1B1 antibody, ATP1B antibody, AT1B1_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ATP1B1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Purification method Purified by affinity chromatography


Target

Target Name ATP1B1
SwissProt ID Link P05026
Function This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
Subcellular Location Cell membrane; Single-pass type II membrane protein.
Tissue Specificity Found in most tissues.
Subunit Structure Composed of three subunits: alpha (catalytic), beta and gamma. Interacts with NKAIN1, NKAIN2 and NKAIN4. Interacts with MLC1. Part of a complex containing MLC1, TRPV4, AQP4 and HEPACAM.
Sequence Similarities Belongs to the X(+)/potassium ATPases subunit beta family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.