Anti-ATOH7 antibody (AA39335)


Alternative names Protein atonal homolog 7, Class A basic helix-loop-helix protein 13, bHLHa13, Helix-loop-helix protein hATH-5, hATH5, ATOH7, ATH5, ATOH7_HUMAN
Species Reactivity Human
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Product name Anti-ATOH7 antibody (AA39335)
Catalog number AA39335
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Protein atonal homolog 7 antibody, Class A basic helix-loop-helix protein 13 antibody, bHLHa13 antibody, Helix-loop-helix protein hATH-5 antibody, hATH5 antibody, ATOH7 antibody, ATH5 antibody, ATOH7_HUMAN antibody

Biological Information

Immunogen Recombinant protein of human ATOH7
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target Name ATOH7
SwissProt ID Link Q8N100
Function Transcription factor involved in the differentiation of retinal ganglion cells.
Subcellular Location Nucleus.
Involvement in Disease Persistent hyperplastic primary vitreous, autosomal recessive: A developmental eye malformation associated with microphthalmia, cataract, glaucoma, and congenital retinal non-attachment. It is due to failure of the primary vitreous to regress in utero, resulting in the presence of a retrolental fibrovascular membrane with persistence of the posterior portion of the tunica vasculosa lentis and hyaloid artery. Disease manifestations range from a trivial remnant of hyaloid vessels to a dense fibrovascular mass causing lens opacity and retinal detachment. The disease is caused by mutations affecting the gene represented in this entry. A 6.5 kb deletion that spans a remote cis regulatory element 20 kb upstream from ATOH7 has been found in PHPVAR patients .
Sequence Similarities Contains 1 bHLH (basic helix-loop-helix) domain.

Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3

Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.