Anti-ATOH1 antibody (AA37215)

$187.00


Alternative names Protein atonal homolog 1, Class A basic helix-loop-helix protein 14, bHLHa14, Helix-loop-helix protein hATH-1, hATH1, ATOH1, ATH1, ATOH1_HUMAN
Species Reactivity Human
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ATOH1 antibody (AA37215)
Catalog number AA37215
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Protein atonal homolog 1 antibody, Class A basic helix-loop-helix protein 14 antibody, bHLHa14 antibody, Helix-loop-helix protein hATH-1 antibody, hATH1 antibody, ATOH1 antibody, ATH1 antibody, ATOH1_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ATOH1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Purification method Purified by affinity chromatography


Target

Target Name ATOH1
SwissProt ID Link Q92858
Function Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
Subcellular Location Nucleus.
Subunit Structure Efficient DNA binding requires dimerization with another bHLH protein.
Sequence Similarities Contains 1 bHLH (basic helix-loop-helix) domain.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.