Anti-ATG9A antibody (AA41461)

$187.00


Alternative names Autophagy-related protein 9A, APG9-like 1, mATG9, ATG9A, APG9L1, ATG9A_HUMAN, Q7Z3C6, 79065
Source 839
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ATG9A antibody (AA41461)
Catalog number AA41461
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Autophagy-related protein 9A antibody, APG9-like 1 antibody, mATG9 antibody, ATG9A antibody, APG9L1 antibody, ATG9A_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target

Target Name ATG9A
SwissProt ID Link Q7Z3C6
Function Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.
Subcellular Location Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1.
Subunit Structure Interacts with SUPT20H.
Sequence Similarities Belongs to the ATG9 family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.