Anti-ASPA antibody (AA39329)


Alternative names Aspartoacylase, EC, Aminoacylase-2, ACY-2, ASPA, ACY2, ASP, ACY2_HUMAN, P45381, 443
Source 313
Species Reactivity Human
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Product name Anti-ASPA antibody (AA39329)
Catalog number AA39329
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Aspartoacylase antibody, EC antibody, Aminoacylase-2 antibody, ACY-2 antibody, ASPA antibody, ACY2 antibody, ASP antibody, ACY2_HUMAN antibody

Biological Information

Immunogen Recombinant protein of human ASPA
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target Name ASPA
SwissProt ID Link P45381
Function Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.
Subcellular Location Cytoplasm. Nucleus.
Involvement in Disease Canavan disease: A rare neurodegenerative condition of infancy or childhood characterized by white matter vacuolization and demyelination that gives rise to a spongy appearance. The clinical features are onset in early infancy, atonia of neck muscles, hypotonia, hyperextension of legs and flexion of arms, blindness, severe mental defect, megalocephaly, and death by 18 months on the average. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Brain white matter, skeletal muscle, kidney, adrenal glands, lung and liver.
Subunit Structure Homodimer.
Sequence Similarities Belongs to the AspA/AstE family. Aspartoacylase subfamily.

Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3

Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.