Anti-ASMT antibody (AA37212)

$187.00


Alternative names Acetylserotonin O-methyltransferase, EC 2.1.1.4, Hydroxyindole O-methyltransferase, HIOMT, ASMT, ASMT_HUMAN, P46597, 438
Source 345?298?
Species Reactivity Human
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ASMT antibody (AA37212)
Catalog number AA37212
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Acetylserotonin O-methyltransferase antibody, EC 2.1.1.4 antibody, Hydroxyindole O-methyltransferase antibody, HIOMT antibody, ASMT antibody, ASMT_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ASMT
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target

Target Name ASMT
SwissProt ID Link P46597
Function Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity.
Tissue Specificity Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level (PubMed:7989373), and not at the protein level (PubMed:8574683).
Subunit Structure Homodimer.
Sequence Similarities Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.