Anti-ASCC3 antibody (AA41359)

$187.00


Alternative names Activating signal cointegrator 1 complex subunit 3, EC 3.6.4.12, ASC-1 complex subunit p200, ASC1p200, Helicase, ATP binding 1, Trip4 complex subunit p200, ASCC3, HELIC1, ASCC3_HUMAN, Q8N3C0, 10973
Source 2202?111?
Species Reactivity Human
Applications WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ASCC3 antibody (AA41359)
Catalog number AA41359
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Activating signal cointegrator 1 complex subunit 3 antibody, EC 3.6.4.12 antibody, ASC-1 complex subunit p200 antibody, ASC1p200 antibody, Helicase, ATP binding 1 antibody, Trip4 complex subunit p200 antibody, ASCC3 antibody, HELIC1 antibody, ASCC3_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ASCC3
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target

Target Name ASCC3
SwissProt ID Link Q8N3C0
Function 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.
Subcellular Location Nucleus. Cytoplasm.
Tissue Specificity Ubiquitous.
Subunit Structure Part of TRIP4 complex, that contains ASCC1, ASCC2 and ASCC3. The TRIP4 complex interacts with ALKBH3.
Sequence Similarities Belongs to the helicase family. Contains 2 helicase ATP-binding domains. Contains 2 helicase C-terminal domains. Contains 2 SEC63 domains.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.