Anti-ARTN antibody (AA27551)

$187.00


Alternative names Artemin, Enovin, Neublastin, ARTN, EVN, ARTN_HUMAN
Species Reactivity Human, Mouse
Applications WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ARTN antibody (AA27551)
Catalog number AA27551
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Artemin antibody, Enovin antibody, Neublastin antibody, ARTN antibody, EVN antibody, ARTN_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target

Target Name ARTN
SwissProt ID Link Q5T4W7
Function Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.
Subcellular Location Secreted.
Tissue Specificity Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain.
Subunit Structure Homodimer; disulfide-linked. Binds to RET.
Sequence Similarities Belongs to the TGF-beta family. GDNF subfamily.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.