Anti-ARMET antibody (AA38570)

$187.00


Alternative names Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich protein, Protein ARMET, MANF, ARMET, ARP, MANF_HUMAN, P55145, 7873
Source 182
Species Reactivity Human, Mouse, Rat
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ARMET antibody (AA38570)
Catalog number AA38570
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Mesencephalic astrocyte-derived neurotrophic factor antibody, Arginine-rich protein antibody, Protein ARMET antibody, MANF antibody, ARMET antibody, ARP antibody, MANF_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human MANF
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target

Target Name ARMET
SwissProt ID Link P55145
Function Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Subcellular Location Secreted.
Post-Translational Modification May contain sialic acid residues.
Sequence Similarities Belongs to the ARMET family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.