Anti-ARHGEF9 antibody (AA29744)

$287.00


Alternative names Rho guanine nucleotide exchange factor 9, Collybistin, PEM-2 homolog, Rac/Cdc42 guanine nucleotide exchange factor 9, ARHGEF9, ARHDH9, KIAA0424, ARHG9_HUMAN, O43307, 23229
Source 516
Species Reactivity Human, Mouse, Rat
Applications WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ARHGEF9 antibody (AA29744)
Catalog number AA29744
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Rho guanine nucleotide exchange factor 9 antibody, Collybistin antibody, PEM-2 homolog antibody, Rac/Cdc42 guanine nucleotide exchange factor 9 antibody, ARHGEF9 antibody, ARHDH9 antibody, KIAA0424 antibody, ARHG9_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target

Target Name ARHGEF9
SwissProt ID Link O43307
Function Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
Subcellular Location Cytoplasm.
Involvement in Disease Epileptic encephalopathy, early infantile, 8: A disorder characterized by hyperekplexia and early infantile epileptic encephalopathy. Neurologic features include exaggerated startle response, seizures, impaired psychomotor development, and mental retardation. Seizures can be provoked by tactile stimulation or extreme emotion. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Detected in brain. Detected at low levels in heart.
Subunit Structure Interacts with GPHN.
Sequence Similarities Contains 1 DH (DBL-homology) domain. Contains 1 PH domain. Contains 1 SH3 domain.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.