Anti-ARG2 antibody (AA36706)

$187.00


Alternative names Arginase-2, mitochondrial, EC 3.5.3.1, Kidney-type arginase, Non-hepatic arginase, Type II arginase, ARG2, ARGI2_HUMAN, P78540, 384
Source 354
Species Reactivity Human
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ARG2 antibody (AA36706)
Catalog number AA36706
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Arginase-2, mitochondrial antibody, EC 3.5.3.1 antibody, Kidney-type arginase antibody, Non-hepatic arginase antibody, Type II arginase antibody, ARG2 antibody, ARGI2_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ARG2
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Purification method Purified by affinity chromatography


Target

Target Name ARG2
SwissProt ID Link P78540
Function May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Subcellular Location Mitochondrion.
Tissue Specificity Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
Subunit Structure Homotrimer.
Sequence Similarities Belongs to the arginase family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.