Anti-APRT antibody (AA34512)

$187.00


Alternative names Adenine phosphoribosyltransferase, APRT, EC 2.4.2.7, APT_HUMAN
Species Reactivity Human, Mouse, Rat
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-APRT antibody (AA34512)
Catalog number AA34512
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Adenine phosphoribosyltransferase antibody, APRT antibody, EC 2.4.2.7 antibody, APT_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human APRT
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Purification method Purified by affinity chromatography


Target

Target Name APRT
SwissProt ID Link P07741
Function Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Subcellular Location Cytoplasm.
Involvement in Disease Adenine phosphoribosyltransferase deficiency: An enzymatic deficiency that can lead to urolithiasis and renal failure. Patients have 2,8-dihydroxyadenine urinary stones. The disease is caused by mutations affecting the gene represented in this entry.
Subunit Structure Homodimer.
Sequence Similarities Belongs to the purine/pyrimidine phosphoribosyltransferase family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.