Anti-APRIL antibody (AA23945)

$187.00


Alternative names Tumor necrosis factor ligand superfamily member 13, A proliferation-inducing ligand, APRIL, TNF- and APOL-related leukocyte expressed ligand 2, TALL-2, TNF-related death ligand 1, TRDL-1, CD antigen CD256, TNFSF13, TALL2, ZTNF2, UNQ383/PRO715, TNF13_HUMAN, O75888, 8741
Source 250?247?
Species Reactivity Human, Mouse, Rat
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-APRIL antibody (AA23945)
Catalog number AA23945
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Tumor necrosis factor ligand superfamily member 13 antibody, A proliferation-inducing ligand antibody, APRIL antibody, TNF- and APOL-related leukocyte expressed ligand 2 antibody, TALL-2 antibody, TNF-related death ligand 1 antibody, TRDL-1 antibody, CD antigen CD256 antibody, TNFSF13 antibody, TALL2 antibody, ZTNF2 antibody, UNQ383/PRO715 antibody, TNF13_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human TNFSF13
Concentration 1mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Purification method Purified by affinity chromatography


Target

Target Name APRIL
SwissProt ID Link O75888
Function Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Subcellular Location Secreted.
Post-Translational Modification The precursor is cleaved by furin.
Tissue Specificity Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Subunit Structure Homotrimer.
Sequence Similarities Belongs to the tumor necrosis factor family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.