Anti-AP3S2 antibody (AA31724)

$287.00


Alternative names AP-3 complex subunit sigma-2, AP-3 complex subunit sigma-3B, Adaptor-related protein complex 3 subunit sigma-2, Sigma-3B-adaptin, Sigma3B-adaptin, Sigma-adaptin 3b, AP3S2, AP3S2_HUMAN, P59780, 10239
Source 193
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AP3S2 antibody (AA31724)
Catalog number AA31724
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names AP-3 complex subunit sigma-2 antibody, AP-3 complex subunit sigma-3B antibody, Adaptor-related protein complex 3 subunit sigma-2 antibody, Sigma-3B-adaptin antibody, Sigma3B-adaptin antibody, Sigma-adaptin 3b antibody, AP3S2 antibody, AP3S2_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human AP3S2
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:1000-1:2000 IHC 1:50-1:200
Purification method Purified by affinity chromatography


Target

Target Name AP3S2
SwissProt ID Link P59780
Function Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
Subcellular Location Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Tissue Specificity Present in all adult tissues examined.
Subunit Structure Adaptor protein complex 3 (AP-3) is a heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2). Interacts with AGAP1. AP-3 associates with the BLOC-1 complex.
Sequence Similarities Belongs to the adaptor complexes small subunit family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.