Anti-AMPD3 antibody (AA36703)

$187.00


Alternative names AMP deaminase 3, EC 3.5.4.6, AMP deaminase isoform E, Erythrocyte AMP deaminase, AMPD3, AMPD3_HUMAN, Q01432, 272
Source 767
Species Reactivity Human
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AMPD3 antibody (AA36703)
Catalog number AA36703
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names AMP deaminase 3 antibody, EC 3.5.4.6 antibody, AMP deaminase isoform E antibody, Erythrocyte AMP deaminase antibody, AMPD3 antibody, AMPD3_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human AMPD3
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target

Target Name AMPD3
SwissProt ID Link Q01432
Function AMP deaminase plays a critical role in energy metabolism.
Involvement in Disease Adenosine monophosphate deaminase deficiency erythrocyte type: A metabolic disorder due to lack of activity of the erythrocyte isoform of AMP deaminase. It is a clinically asymptomatic condition characterized by a 50% increase in steady-state levels of ATP in affected cells. Individuals with complete deficiency of erythrocyte AMP deaminase are healthy and have no hematologic disorders. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Isoform 1 is the predominant form in skeletal muscle; Isoform 2 predominates in smooth muscle, non-muscle tissue, embryonic muscle and undifferentiated myoblasts; Isoform 3 is found in erythrocytes.
Subunit Structure Homotetramer.
Sequence Similarities Belongs to the adenosine and AMP deaminases family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.