Anti-AMIGO2 antibody (AA33961)

$287.00


Alternative names Amphoterin-induced protein 2, AMIGO-2, Alivin-1, Differentially expressed in gastric adenocarcinomas, DEGA, AMIGO2, ALI1, AMGO2_HUMAN, Q86SJ2, 347902
Source 522
Species Reactivity Human, Mouse, Rat
Applications WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AMIGO2 antibody (AA33961)
Catalog number AA33961
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Amphoterin-induced protein 2 antibody, AMIGO-2 antibody, Alivin-1 antibody, Differentially expressed in gastric adenocarcinomas antibody, DEGA antibody, AMIGO2 antibody, ALI1 antibody, AMGO2_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human AMIGO2
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500-1:2000
Purification method Purified by affinity chromatography


Target

Target Name AMIGO2
SwissProt ID Link Q86SJ2
Function Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Nucleus. Associated with nucleus as well as plasma membrane. Restricted to somata of cerebellar as well as hippocampal neurons.
Tissue Specificity Highest levels in breast, ovary, cervix, and uterus. Lower levels in lung, colon, and rectum. Differentially expressed in 56% of thyroid, 57% of pancreatic and 45% of stomach cancers.
Subunit Structure Binds itself as well as AMIGO1 and AMIGO3.
Sequence Similarities Belongs to the immunoglobulin superfamily. AMIGO family. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.