Anti-ALG1 antibody (AA33023)


Alternative names Chitobiosyldiphosphodolichol beta-mannosyltransferase, EC, Asparagine-linked glycosylation protein 1 homolog, Beta-1,4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase, Mannosyltransferase-1, MT-1, hMat-1, ALG1, HMAT1, HMT1, PSEC0061, UNQ861/PRO1870, ALG1_HUMAN, Q9BT22, 56052
Source 464
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Product name Anti-ALG1 antibody (AA33023)
Catalog number AA33023
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Chitobiosyldiphosphodolichol beta-mannosyltransferase antibody, EC antibody, Asparagine-linked glycosylation protein 1 homolog antibody, Beta-1,4-mannosyltransferase antibody, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase antibody, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase antibody, Mannosyltransferase-1 antibody, MT-1 antibody, hMat-1 antibody, ALG1 antibody, HMAT1 antibody, HMT1 antibody, PSEC0061 antibody, UNQ861/PRO1870 antibody, ALG1_HUMAN antibody

Biological Information

Immunogen Recombinant protein of human ALG1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500-1:2000 IHC 1:50-1:200
Purification method Purified by affinity chromatography


Target Name ALG1
SwissProt ID Link Q9BT22
Function Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
Subcellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Involvement in Disease Congenital disorder of glycosylation 1K: A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. The disease is caused by mutations affecting the gene represented in this entry.
Sequence Similarities Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 33 subfamily.

Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3

Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.