Anti-ALDOB antibody (AA29894)

$287.00


Alternative names Fructose-bisphosphate aldolase B, EC 4.1.2.13, Liver-type aldolase, ALDOB, ALDB, ALDOB_HUMAN, P05062, 229
Source 364
Species Reactivity Human, Mouse, Rat
Applications IF/ICC, IP, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ALDOB antibody (AA29894)
Catalog number AA29894
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Fructose-bisphosphate aldolase B antibody, EC 4.1.2.13 antibody, Liver-type aldolase antibody, ALDOB antibody, ALDB antibody, ALDOB_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ALDOB
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 IP 1:20 - 1:50
Purification method Purified by affinity chromatography


Target

Target Name ALDOB
SwissProt ID Link P05062
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Involvement in Disease Hereditary fructose intolerance: Autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life. The disease is caused by mutations affecting the gene represented in this entry.
Subunit Structure Homotetramer. Interacts with BBS1, BBS2, BBS4 and BBS7.
Sequence Similarities Belongs to the class I fructose-bisphosphate aldolase family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.