Anti-ALDH6A1 antibody (AA28727)

$287.00


Alternative names Methylmalonate-semialdehyde dehydrogenase, mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase, EC 1.2.1.18, EC 1.2.1.27, Aldehyde dehydrogenase family 6 member A1, ALDH6A1, MMSA_HUMAN, Q02252, 4329
Source 535
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ALDH6A1 antibody (AA28727)
Catalog number AA28727
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Methylmalonate-semialdehyde dehydrogenase, mitochondrial antibody, MMSDH antibody, Malonate-semialdehyde dehydrogenase antibody, EC 1.2.1.18 antibody, EC 1.2.1.27 antibody, Aldehyde dehydrogenase family 6 member A1 antibody, ALDH6A1 antibody, MMSA_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ALDH6A1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Purification method Purified by affinity chromatography


Target

Target Name ALDH6A1
SwissProt ID Link Q02252
Function Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Subcellular Location Mitochondrion.
Involvement in Disease Methylmalonate semialdehyde dehydrogenase deficiency: A metabolic disorder characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. The disease is caused by mutations affecting the gene represented in this entry.
Subunit Structure Homotetramer.
Sequence Similarities Belongs to the aldehyde dehydrogenase family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.