Anti-ALDH1A3 antibody (AA27425)

$187.00


Alternative names Aldehyde dehydrogenase family 1 member A3, EC 1.2.1.5, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, RalDH3, ALDH1A3, ALDH6, AL1A3_HUMAN, P47895, 220
Source 512
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ALDH1A3 antibody (AA27425)
Catalog number AA27425
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Aldehyde dehydrogenase family 1 member A3 antibody, EC 1.2.1.5 antibody, Aldehyde dehydrogenase 6 antibody, Retinaldehyde dehydrogenase 3 antibody, RALDH-3 antibody, RalDH3 antibody, ALDH1A3 antibody, ALDH6 antibody, AL1A3_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target

Target Name ALDH1A3
SwissProt ID Link P47895
Function Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system.
Subcellular Location Cytoplasm.
Involvement in Disease Microphthalmia, isolated, 8: A disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, and other abnormalities may also be present. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Sequence Similarities Belongs to the aldehyde dehydrogenase family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.