Anti-Albumin antibody [clone 6T4/N6] (AA22568)

$287.00


Alternative names Serum albumin, ALB, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, ALBU_HUMAN, P02768, 213
Source 609
Species Reactivity Human, Mouse
Applications WB
Host Murine
Class Monoclonal
Conjugated Unconjugated


Description

Product name Anti-Albumin antibody [clone 6T4/N6] (AA22568)
Catalog number AA22568
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Serum albumin antibody, ALB antibody, GIG20 antibody, GIG42 antibody, PRO0903 antibody, PRO1708 antibody, PRO2044 antibody, PRO2619 antibody, PRO2675 antibody, UNQ696/PRO1341 antibody, ALBU_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Clone 6T4/N6
Purification method Purified by affinity chromatography


Target

Target Name Albumin
SwissProt ID Link P02768
Function Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Subcellular Location Secreted.
Involvement in Disease Hyperthyroxinemia, familial dysalbuminemic: A disorder characterized by abnormally elevated levels of total serum thyroxine: A rare autosomal recessive disorder manifested by the presence of a very low amount of circulating serum albumin. Affected individuals manifest mild edema, hypotension, fatigue, and, occasionally, lower body lipodystrophy . The most common biochemical finding is hyperlipidemia, with a significant increase in the total and LDL cholesterol concentrations, but normal concentrations of HDL cholesterol and triglycerides. The disease is caused by mutations affecting the gene represented in this entry.
Post-Translational Modification Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracellular medium.Acetylated on Lys-223 by acetylsalicylic acid.
Tissue Specificity Plasma.
Sequence Similarities Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.