Anti-AIPL1 antibody (AA37015)

$187.00


Alternative names Aryl-hydrocarbon-interacting protein-like 1, AIPL1, AIPL2, AIPL1_HUMAN, Q9NZN9, 23746
Source 384
Species Reactivity Human
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AIPL1 antibody (AA37015)
Catalog number AA37015
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Aryl-hydrocarbon-interacting protein-like 1 antibody, AIPL1 antibody, AIPL2 antibody, AIPL1_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human AIPL1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target

Target Name AIPL1
SwissProt ID Link Q9NZN9
Function May be important in protein trafficking and/or protein folding and stabilization.
Subcellular Location Cytoplasm. Nucleus.
Involvement in Disease Leber congenital amaurosis 4: A severe dystrophy of the retina, typically becoming evident in the first years of life. Visual function is usually poor and often accompanied by nystagmus, sluggish or near-absent pupillary responses, photophobia, high hyperopia and keratoconus. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Highly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.
Subunit Structure Interacts with NUB1.
Sequence Similarities Contains 1 PPIase FKBP-type domain. Contains 3 TPR repeats.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.