Anti-AGPAT2 antibody (AA37179)

$187.00


Alternative names 1-acyl-sn-glycerol-3-phosphate acyltransferase beta, EC 2.3.1.51, 1-acylglycerol-3-phosphate O-acyltransferase 2, 1-AGP acyltransferase 2, 1-AGPAT 2, Lysophosphatidic acid acyltransferase beta, LPAAT-beta, AGPAT2, PLCB_HUMAN, O15120, 10555
Source 278
Species Reactivity Human
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AGPAT2 antibody (AA37179)
Catalog number AA37179
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names 1-acyl-sn-glycerol-3-phosphate acyltransferase beta antibody, EC 2.3.1.51 antibody, 1-acylglycerol-3-phosphate O-acyltransferase 2 antibody, 1-AGP acyltransferase 2 antibody, 1-AGPAT 2 antibody, Lysophosphatidic acid acyltransferase beta antibody, LPAAT-beta antibody, AGPAT2 antibody, PLCB_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human AGPAT2
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target

Target Name AGPAT2
SwissProt ID Link O15120
Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Involvement in Disease Congenital generalized lipodystrophy 1: An autosomal recessive disorder characterized by a near complete absence of adipose tissue, extreme insulin resistance, hypertriglyceridemia, hepatic steatosis and early onset of diabetes. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Expressed predominantly in adipose tissue, pancreas and liver.
Sequence Similarities Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.