Anti-AGFG1 antibody (AA36529)

$187.00


Alternative names Arf-GAP domain and FG repeat-containing protein 1, HIV-1 Rev-binding protein, Nucleoporin-like protein RIP, Rev-interacting protein, Rev/Rex activation domain-binding protein, AGFG1, HRB, RAB, RIP, AGFG1_HUMAN, P52594, 3267
Source 562
Species Reactivity Human, Mouse, Rat
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-AGFG1 antibody (AA36529)
Catalog number AA36529
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Arf-GAP domain and FG repeat-containing protein 1 antibody, HIV-1 Rev-binding protein antibody, Nucleoporin-like protein RIP antibody, Rev-interacting protein antibody, Rev/Rex activation domain-binding protein antibody, AGFG1 antibody, HRB antibody, RAB antibody, RIP antibody, AGFG1_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human AGFG1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Purification method Purified by affinity chromatography


Target

Target Name AGFG1
SwissProt ID Link P52594
Function Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Subcellular Location Nucleus. Cytoplasmic vesicle.
Post-Translational Modification O-glycosylated.
Tissue Specificity Ubiquitously expressed.
Subunit Structure Interacts with EPS15R and EPS15. Interacts with FCHO1.
Sequence Similarities Contains 1 Arf-GAP domain.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.