Anti-ADAP1 antibody (AA31967)

$287.00


Alternative names Arf-GAP with dual PH domain-containing protein 1, Centaurin-alpha-1, Cnt-a1, Putative MAPK-activating protein PM25, ADAP1, CENTA1, ADAP1_HUMAN
Species Reactivity Human, Mouse, Rat
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ADAP1 antibody (AA31967)
Catalog number AA31967
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Arf-GAP with dual PH domain-containing protein 1 antibody, Centaurin-alpha-1 antibody, Cnt-a1 antibody, Putative MAPK-activating protein PM25 antibody, ADAP1 antibody, CENTA1 antibody, ADAP1_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ADAP1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Purification method Purified by affinity chromatography


Target

Target Name ADAP1
SwissProt ID Link O75689
Function GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Subcellular Location Nucleus. Cytoplasm. Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase.
Post-Translational Modification Phosphorylated by PRKCA, PRKCI, PRKCZ and PRKD1 in vitro.
Tissue Specificity Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.
Subunit Structure Interacts with PRKCA, PRKCI and PRKCZ. Interacts with the N-terminal region of PRKD1.
Sequence Similarities Contains 1 Arf-GAP domain. Contains 2 PH domains.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.