Anti-ACTR5 antibody (AA29285)

$287.00


Alternative names Actin-related protein 5, hARP5, Sarcoma antigen NY-SAR-16, ACTR5, ARP5, ARP5_HUMAN, Q9H9F9, 79913
Source 607
Species Reactivity Human, Mouse, Rat
Applications IF/ICC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ACTR5 antibody (AA29285)
Catalog number AA29285
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Actin-related protein 5 antibody, hARP5 antibody, Sarcoma antigen NY-SAR-16 antibody, ACTR5 antibody, ARP5 antibody, ARP5_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ACTR5
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:1000 - 1:2000 IF 1:50 - 1:100
Purification method Purified by affinity chromatography


Target

Target Name ACTR5
SwissProt ID Link Q9H9F9
Function Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in DNA double-strand break repair and UV-damage excision repair.
Subcellular Location Nucleus. Cytoplasm. Predominantly nuclear but undergoes nucleo-cytoplasmic shuttling. Localized to interphase nuclei, but not nucleoli; excluded from chromosomes as mitosis progresses.
Subunit Structure Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Interacts with DDB1. Interacts with ACTR8; the interaction is observed in asynchronous (interphase) cells but not in metaphase-arrested cells indicative for a possible dissociation of the INO80 complex in mitotic cells.
Sequence Similarities Belongs to the actin family. ARP5 subfamily.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.