Anti-ACTR3B antibody (AA40951)

$187.00


Alternative names Actin-related protein 3B, ARP3-beta, Actin-like protein 3B, Actin-related protein ARP4, ACTR3B, ARP11, ARP4, ARP3B_HUMAN, Q9P1U1, 57180
Source 418
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ACTR3B antibody (AA40951)
Catalog number AA40951
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Actin-related protein 3B antibody, ARP3-beta antibody, Actin-like protein 3B antibody, Actin-related protein ARP4 antibody, ACTR3B antibody, ARP11 antibody, ARP4 antibody, ARP3B_HUMAN antibody


Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target

Target Name ACTR3B
SwissProt ID Link Q9P1U1
Function Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.
Subcellular Location Cytoplasm, cytoskeleton. Cell projection.
Tissue Specificity Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential.
Subunit Structure Interacts with the Arp2/3 complex composed of ARP2, ARP3, ARPC1B, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.
Sequence Similarities Belongs to the actin family. ARP3 subfamily.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 C. Avoid multiple freeze/thaw cycles.