Anti-ACADM antibody (AA25250)


Alternative names Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, MCAD, EC, ACADM, ACADM_HUMAN, P11310, 34
Source 421
Species Reactivity Human, Mouse, Rat
Applications IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Product name Anti-ACADM antibody (AA25250)
Catalog number AA25250
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Medium-chain specific acyl-CoA dehydrogenase, mitochondrial antibody, MCAD antibody, EC antibody, ACADM antibody, ACADM_HUMAN antibody

Biological Information

Immunogen Recombinant protein of human ACADM
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Purification method Purified by affinity chromatography


Target Name ACADM
SwissProt ID Link P11310
Function This enzyme is specific for acyl chain lengths of 4 to 16.
Subcellular Location Mitochondrion matrix.
Involvement in Disease Acyl-CoA dehydrogenase medium-chain deficiency: An inborn error of mitochondrial fatty acid beta-oxidation which causes fasting hypoglycemia, hepatic dysfunction and encephalopathy, often resulting in death in infancy. The disease is caused by mutations affecting the gene represented in this entry.
Post-Translational Modification Acetylation at Lys-307 and Lys-311 in proximity of the cofactor-binding sites reduces catalytic activity. These sites are deacetylated by SIRT3.
Subunit Structure Homotetramer. Interacts with the heterodimeric electron transfer flavoprotein ETF.
Sequence Similarities Belongs to the acyl-CoA dehydrogenase family.

Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3

Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.