Anti-ABCF1 antibody (AA29864)

$287.00


Alternative names ATP-binding cassette sub-family F member 1, ATP-binding cassette 50, TNF-alpha-stimulated ABC protein, ABCF1, ABC50, ABCF1_HUMAN, Q8NE71, 23
Source 845
Species Reactivity Human, Mouse, Rat
Applications WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ABCF1 antibody (AA29864)
Catalog number AA29864
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names ATP-binding cassette sub-family F member 1 antibody, ATP-binding cassette 50 antibody, TNF-alpha-stimulated ABC protein antibody, ABCF1 antibody, ABC50 antibody, ABCF1_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ABCF1
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:500 - 1:2000
Purification method Purified by affinity chromatography


Target

Target Name ABCF1
SwissProt ID Link Q8NE71
Function Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Subcellular Location Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
Post-Translational Modification Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes.
Tissue Specificity Ubiquitous.
Subunit Structure Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes.
Sequence Similarities Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. Contains 2 ABC transporter domains.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.