Anti-ABCB9 antibody (AA32180)

$287.00


Alternative names ATP-binding cassette sub-family B member 9, ATP-binding cassette transporter 9, ABC transporter 9 protein, hABCB9, TAP-like protein, TAPL, ABCB9, KIAA1520, ABCB9_HUMAN, Q9NP78, 23457
Source 766
Species Reactivity Human, Mouse
Applications IF/ICC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Description

Product name Anti-ABCB9 antibody (AA32180)
Catalog number AA32180
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names ATP-binding cassette sub-family B member 9 antibody, ATP-binding cassette transporter 9 antibody, ABC transporter 9 protein antibody, hABCB9 antibody, TAP-like protein antibody, TAPL antibody, ABCB9 antibody, KIAA1520 antibody, ABCB9_HUMAN antibody


Biological Information

Immunogen Recombinant protein of human ABCB9
Concentration 1 mg/ml
Isotype IgG
Application Notes WB 1:200-1:2000 IF 1:50-1:100
Purification method Purified by affinity chromatography


Target

Target Name ABCB9
SwissProt ID Link Q9NP78
Function ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.
Subcellular Location Lysosome membrane; Multi-pass membrane protein. May be located in membrane rafts.
Tissue Specificity Highly expressed in testis, and at moderate levels in brain, spinal cord, and thyroid. Not expressed in monocytes but strongly expressed during differentiation of monocytes to dendritic cells and macrophages.
Subunit Structure Homodimer.
Sequence Similarities Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.


Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3


Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.