Anti-AAAS antibody (AA36922)


Alternative names Aladin, Adracalin, AAAS, ADRACALA, GL003, AAAS_HUMAN
Species Reactivity Human
Applications IF/ICC, IHC, WB
Host Rabbit
Class Polyclonal
Conjugated Unconjugated


Product name Anti-AAAS antibody (AA36922)
Catalog number AA36922
Brand family Ango
Product type Primary Antibody
Antibody Alternative Names Aladin antibody, Adracalin antibody, AAAS antibody, ADRACALA antibody, GL003 antibody, AAAS_HUMAN antibody

Biological Information

Concentration 1 mg/ml
Isotype IgG
Purification method Purified by affinity chromatography


Target Name AAAS
SwissProt ID Link Q9NRG9
Function Plays a role in the normal development of the peripheral and central nervous system.
Subcellular Location Nucleus, nuclear pore complex.
Involvement in Disease Achalasia-addisonianism-alacrima syndrome: An autosomal recessive disorder characterized by adreno-corticotropic hormone -resistant adrenal failure, achalasia of the esophageal cardia and alacrima. The syndrome is associated with variable and progressive neurological impairment involving the central, peripheral, and autonomic nervous system. Other features such as palmoplantar hyperkeratosis, short stature, facial dysmorphy and osteoporosis may also be present. The disease is caused by mutations affecting the gene represented in this entry.
Tissue Specificity Widely expressed. Particularly abundant expression is found in cerebellum, corpus callosum, adrenal gland, pituitary gland, gastrointestinal structures and fetal lung.
Subunit Structure Interacts with NDC1, the interaction is required for nuclear pore localization.
Sequence Similarities Contains 7 WD repeats.

Poduct Presentation

Form Liquid
Preservative 0.02% (w/v) sodium azide
Storage buffer PBS with 50% glycerol, pH 7.3

Storage and Shipping Information

Storage Store at -20 or -80 C. Avoid multiple freeze/thaw cycles.